ENST00000619449

Human non-coding transcript

Reference

Relation to reference Complete match of intron chain
Reference ENSEMBL ID ENST00000619449
Reference alias MALAT1
Biotype of reference transcript lincRNA
Reference Gene ID ENSG00000251562
Responsive image

Isoforms

ENSG00000251562 MSTRG.22374.97 MSTRG.22375.13 MSTRG.22375.14 MSTRG.22375.19 ENST00000544868 MSTRG.22374.32 MSTRG.22374.15 MSTRG.22374.103 MSTRG.22374.72 MSTRG.22374.13 MSTRG.22374.55 MSTRG.22374.56 MSTRG.22374.50 MSTRG.22374.52 MSTRG.22374.59 MSTRG.22374.38 ENST00000618925 MSTRG.22375.87 MSTRG.22375.81 MSTRG.22375.62 MSTRG.22375.69 MSTRG.22375.44 MSTRG.22375.49 ENST00000617791 MSTRG.22375.28 MSTRG.22375.22 MSTRG.22375.20 MSTRG.22375.21 ENST00000619449 ENST00000616691 MSTRG.22374.83 ENST00000610851 MSTRG.22374.138 ENST00000618132 MSTRG.22374.116 MSTRG.22374.117 MSTRG.22374.119 MSTRG.22374.69 MSTRG.22375.97 MSTRG.22374.12 MSTRG.22374.144 ENST00000616527 ENST00000620902 MSTRG.22375.2 MSTRG.22375.56 MSTRG.22375.52 ENST00000508832 MSTRG.22375.34 MSTRG.22374.6 MSTRG.22374.8 MSTRG.22374.9
Responsive image

lncRNA

Transcript ID ENST00000619449
Chromosome 11
Start 65497766
Stop 65499609
Strand +
Exons 3
Length 794 nt
Protein coding potential Low

Expession

Sample ID Sample type Expression (TPM)
ENCSR000AEPK5622515.212263
ENCSR000AEGGM128781847.392879
ENCSR000AEQK562630.950981
ENCSR000AEHGM12878369.466619
ENCSR309HXKHepG20.21628699999999998
ENCSR925SYZHepG20.109051
Responsive image

FASTA

>ENST00000619449
AGGACTGGGGCCCCGCAACTGGCCTCTCCTGCCCTCTTAAGCGCAGCGCCATTTTAGCAACGCAGAAGCCCGGCGCCGGGAAGCCTCAGCTCGCCTGAAGGTGGTAAACTATACCTACTGTCCCTCAAGAGAACACAAGAAGTGCTTTAAGAGGCGGCGGAAGGTGATCGAATTCCGGTGATGCGAGTTGTTCTCCGTCTATAAATACGCCTCGCCCGAGCTGTGCGGTAGGCATTGAGGCAGCCAGCGCAGGGGCTTCTGCTGAGGGGGCAGGCGGAGCTTGAGGAAACCGCAGATAAGTTTTTTTCTCTTTGAAAGATAGAGATTAATACAACTACTTAAAAAATATAGTCAATAGGTTACTAAGATATTGCTTAGCGTTAAGTTTTTAACGTAATTTTAATAGCTTAAGATTTTAAGAGAAAATATGAAGACTTAGAAGAGTAGCATGAGGAAGGAAAAGATAAAAGGTTTCTAAAACATGACGGAGGTTGAGATGAAGCTTCTTCATGGAGTAAAAAATGTATTTAAAAGAAAATTGAGAGAAAGGACTACAGAGCCCCGAATTAATACCAATAGAAGGGCAATGCTTTTAGATTAAAATGAAGGTGACTTAAACAGCTTAAAGTTTAGTTTAAAAGTTGTAGGTGATTAAAATAATTTGAAGGCGATCTTTTAAAAAGAGATTAAACCGAAGGTGATTAAAAGACCTTGAAATCCATGACGCAGGGAGAATTGCGTCATTTAAAGCCTAGTTAACGCATTTACTAAACGCAGACGAAAATGGAAAGATT

Disease and interactions

DiseasePMIDDysfunction_typeData source
gallbladder cancer27420766expressionPMC6372806
gastric cancer27887846expressionPMC6372806
renal cell carcinoma25480417expressionPMC6372806
gastric cancer28942451regulatedPMC6372806
endometrial cancer27693631expressionPMC6372806
esophageal cancer25613496regulatedPMC6372806
osteosarcoma25431257regulatedPMC6372806
25773124PMC6372806
hepatocellular carcinoma28469957expressionPMC6372806
osteosarcoma28346809expressionPMC6372806
renal cell carcinoma25600645expressionPMC6372806
28535533expressionPMC6372806
bladder cancer24449823expressionPMC6372806
gastric cancer27259812expressionPMC6372806
breast cancer28915533expressionPMC6372806
breast cancer26917489regulatedPMC6372806
26335021PMC6372806
gastric cancer25280565expressionPMC6372806
hepatocellular carcinoma21678027expressionPMC6372806
colorectal cancer25025966expressionPMC6372806
cholangiocarcinoma28059437expressionPMC6372806
multiple myeloma28295550expressionPMC6372806
tongue cancer28260102expressionPMC6372806
glioma26619802expressionPMC6372806
cervical cancer26242259expressionPMC6372806
colorectal cancer25446987expressionPMC6372806
mantle cell lymphoma27998273expressionPMC6372806
cervical cancer26798987expressionPMC6372806
colorectal cancer28069878expressionPMC6372806
thyroid cancer27470543expressionPMC6372806
bladder cancer28648755expressionPMC6372806
oral squamous cell carcinoma28926115expressionPMC6372806
hepatocellular carcinoma28543721expressionPMC6372806
prostate cancer23845456expressionPMC6372806
gastric cancer28276823expressionPMC6372806
bladder cancer23153939expressionPMC6372806
non-small-cell lung cancer25217850expressionPMC6372806
renal cell carcinoma27655020expressionPMC6372806
choriocarcinoma29096355expressionPMC6372806
oral squamous cell carcinoma26522444expressionPMC6372806
breast cancer27197265expressionPMC6372806
lung cancer23243023expressionPMC6372806
hypertension28056547expressionPMC6372806
hepatocellular carcinoma24468535expressionPMC6372806
pancreatic cancer25269958expressionPMC6372806
osteosarcoma26575981expressionPMC6372806
breast cancer26676637expressionPMC6372806
thyroid cancer28543663expressionPMC6372806
hepatocellular carcinoma28720061expressionPMC6372806
multiple myeloma25187517expressionPMC6372806
tongue cancer27586393expressionPMC6372806
gastric cancer28268166expressionPMC6372806
calcific aortic valve disease28522163expressionPMC6372806
esophageal cancer26493997expressionPMC6372806
pancreatic cancer28701723expressionPMC6372806
osteosarcoma28098894expressionPMC6372806
liver fibrosis26435214expressionPMC6372806
endometrial cancer25085246regulatedPMC6372806
nasopharyngeal carcinoma27584791regulatedPMC6372806
esophageal cancer27935117expressionPMC6372806
colorectal cancer29436635expressionPMC6372806
lung cancer28615056regulatedPMC6372806
esophageal cancer27470544expressionPMC6372806
glioma26938295expressionPMC6372806
osteoarthritis28590075expressionPMC6372806
hepatocellular carcinoma28722813expressionPMC6372806
29051139expressionPMC6372806
gallbladder cancer29058818expressionPMC6372806
retinoblastoma29073720expressionPMC6372806
diabetes mellitus29110299expressionPMC6372806
22487937expressionPMC6372806
multiple myeloma24583225expressionPMC6372806
Parkinson's disease27021022expressionPMC6372806
glioma29202181expressionPMC6372806
osteosarcoma29204769expressionPMC6372806
multiple myeloma29214735expressionPMC6372806
non-small-cell lung cancer29215698expressionPMC6372806
pancreatic cancer29215734expressionPMC6372806
colon cancer29226325expressionPMC6372806
29227193expressionPMC6372806
29258822expressionPMC6372806
29274336expressionPMC6372806
osteosarcoma29290771expressionPMC6372806
esophageal squamous cell carcinoma25538231regulationPMC5753334
gallbladder cancer24658096regulationPMC5753334
colon cancer25546229regulationPMC5753334
colorectal cancer25031737regulationPMC5753334
bladder cancer24373479regulationPMC5753334
breast cancer22492512regulationPMC5753334
breast cancer22996375regulationPMC5753334
breast cancer24499465regulationPMC5753334
cancer23463798regulationPMC5753334
cancer24757675regulationPMC5753334
tumor24721780regulationPMC5753334
prostate cancer23726266PMC5753334
cervical cancer24932303PMC5753334
pancreatic ductal adenocarcinoma24815433PMC5753334
nasopharyngeal carcinoma23688988PMC5753334
bladder cancer22722759PMC5753334
gastric cancer24857172PMC5753334
colorectal cancer24244343PMC5753334
melanoma24892958PMC5753334
breast cancer24525122PMC5753334
neuroblastoma24742640PMC5753334
prostate cancer22349460PMC5753334
osteosarcoma17660802PMC5753334
non-small cell lung cancer24313945PMC5753334
multiple myeloma25369863PMC5753334
breast cancer26918449PMC5753334
breast cancer 26926567PMC5753334
gastric cancer 26871474PMC5753334
acute myocardial infarction25035150PMC5753334
diabetes mellitus25356875PMC5753334
glioblastoma25772239PMC5753334
ovarian cancer24379988PMC5753334
esophageal squamous cell carcinoma27015363PMC5753334
colorectal cancer21503572PMC5753334
lung cancer22491206PMC5753334
hepatocelluar carcinoma22493738mutationPMC5753334
paraspeckle disintegration19188602mutationPMC5753334
renal cancer26461224interactionPMC5753334
nasopharyngeal carcinoma26482776interactionPMC5753334
cervical cancer26311052interactionPMC5753334
non-small cell lung cancer26265046interactionPMC5753334
lung cancer26415832interactionPMC5753334
"hepatocellular carcinoma
prostate cancer26516927interactionPMC5753334
cervical cancer20213048InteractionPMC5753334
non-small-cell lung cancer25036876interactionPMC5753334
breast cancer26191181interactionPMC5753334
pre-eclampsia26722461interactionPMC5753334
breast cancer26275461interactionPMC5753334
glioma26649728interactionPMC5753334
lung adenocarcinoma20937273interactionPMC5753334
cervical cancer26400521expressionPMC5753334
proliferative vitreoretinopathy26241674expressionPMC5753334
gastric cancer26096073expressionPMC5753334
non-small cell lung cancer26131129expressionPMC5753334
non-small cell lung cancer22088988expressionPMC5753334
triple-negative breast cancer25996380expressionPMC5753334
hepatocelluar carcinoma16878148expressionPMC5753334
pancreatic cancer25811929expressionPMC5753334
pituitary adenoma24469926expressionPMC5753334
pancreatic cancer25481511expressionPMC5753334
glioma25613066expressionPMC5753334
non-small cell lung cancer12970751expressionPMC5753334
esophageal squamous cell carcinoma26406400expressionPMC5753334
laryngeal squamous cell carcinoma25257554expressionPMC5753334
endometrial stromal sarcoma16441420expressionPMC5753334
bladder cancer24006935expressionPMC5753334
cancer20711585expressionPMC5753334
cancer20864030expressionPMC5753334
cancer23660942expressionPMC5753334
decreased myogenesis23485710expressionPMC5753334
diabetes mellitus24436191expressionPMC5753334
hepatocelluar carcinoma17006932expressionPMC5753334
hepatocelluar carcinoma24183851expressionPMC5753334
lung adenocarcinoma19690017expressionPMC5753334
lung cancer24667321expressionPMC5753334
non-small cell lung cancer21550244expressionPMC5753334
non-small cell lung cancer21903344expressionPMC5753334
non-small cell lung cancer22817756expressionPMC5753334
osteosarcoma20951849expressionPMC5753334
small cell lung cancer22928560expressionPMC5753334
papillary thyroid carcinoma25997963expressionPMC5753334
neuroblastoma20149803expressionPMC5753334
lung cancer26137228expressionPMC5753334
laryngeal squamous cell carcinoma24817925expressionPMC5753334
Responsive image
Level of interactionTypeTargetPMIDData source
DNA-TFregulationCREB20149803PMC5753334
RNA-ProteinbindingSR20797886PMC5753334
RNA-ProteinbindingSR proteins 20797886PMC5753334
RNA-ProteinregulationSR protein family20864030PMC5753334
RNA-ProteinregulationSRSF120864030PMC5753334
RNA-Proteinbindingp54nrb21444682PMC5753334
RNA-ProteinbindingPSF21444682PMC5753334
DNA-ProteinregulationPc222078878PMC5753334
DNA-ProteinregulationPc222078878PMC5753334
RNA-ProteinregulationRNPS122355166PMC5753334
RNA-ProteinregulationSRm16022355166PMC5753334
RNA-ProteinregulationIBP16022355166PMC5753334
RNA-Proteinregulationpre-mRNA splicing factors23698766PMC5753334
RNA-DNAregulationBcl-225036876PMC5753334
RNA-DNAbindingSp1 and LTBP3 promoter25187517PMC5753334
regulationCisplatin and paclitaxel25257554PMC5753334
RNA-RNAregulationSiRNA25280565PMC5753334
RNA-ProteinregulationPI3K/AKT signaling pathway25431257PMC5753334
RNA-RNAregulationmiR-101 and miR-21725538231PMC5753334
RNA-ProteinregulationCCL525546229PMC5753334
RNA-ProteinregulationATM-CHK2 pathway25613496PMC5753334
RNA-ProteinregulationRANKL25817340PMC5753334
regulationPI3K-AKT pathway26191181PMC5753334
RNA-RNAregulationmiRNA-12426242259PMC5753334
RNA-ProteinbindingTDP-4326265046PMC5753334
RNA-RNAregulationhsa-miR-126275461PMC5753334
RNA-RNAregulationmiR-14526311052PMC5753334
DNA-ProteinregulationSp1/326352013PMC5753334
RNA-ProteinregulationEZH2 (enhancer of zeste homolog 2) and H3K27me326415832PMC5753334
DNA-RNAregulationmiR-21726415832PMC5753334
RNA-RNAbindingmiR-200s26461224PMC5753334
RNA-RNAregulationmiR-126482776PMC5753334
RNA-ProteinbindingEZH226516927PMC5753334
RNA-ProteinregulationN-cadherin, Vimentin, E-cadherin26522444PMC5753334
RNA-ProteinregulationZO-1, occludin and claudin-526619802PMC5753334
RNA-RNAregulationmiR-14026619802PMC5753334
regulationERK/MAPK signaling26649728PMC5753334
RNA-ProteinregulationSox2 and Nestin26649728PMC5753334
RNA-RNAregulationHsa-miR-126676637PMC5753334
RNA-Proteinregulationpro-apoptotic proteins including cleaved caspase-3, cleaved caspase-9 and cleaved poly (ADP-ribose) 26722461PMC5753334
RNA-DNAregulationPCDH1026871474PMC5753334
RNA-ProteinbindingEZH226871474PMC5753334
RNA-RNAbindingmiR-124 26918449PMC5753334
RNA-DNAregulationcyclin-dependent kinase 4 (CDK4)26918449PMC5753334
RNA-DNAregulationcdc4226926567PMC5753334
RNA-RNAbindingmiR-1 26926567PMC5753334

Conservation

Conserved in: 10 species
Not found in: 1 species
Most distant counterpart in: Marmoset
Conserved species: Chimp, Bonobo, Gorilla, Orangutan, Rhesus, Crab-eating macaque, Atys, Baboon, Green monkey, Marmoset
Not found in: Lemur
Responsive image
You are here

Human

ENST00000619449

Counterpart found

Chimp

TCONS_00020731

Exonic Identity 79%

Locus Identity 34%
Counterpart found

Bonobo

TCONS_00022393

Exonic Identity 71%

Locus Identity 30%
Counterpart found

Gorilla

TCONS_00005532

Exonic Identity 0%

Locus Identity 0%
Counterpart found

Orangutan

TCONS_00007273

Exonic Identity 0%

Locus Identity 0%
Counterpart found

Rhesus

TCONS_00069425

Exonic Identity 0%

Locus Identity 0%
Counterpart found

MacacaFascicularis

TCONS_00108125

Exonic Identity 0%

Locus Identity 91%
Counterpart found

Atys

TCONS_00089607

Exonic Identity 0%

Locus Identity 91%
Counterpart found

Baboon

TCONS_00052525

Exonic Identity 0%

Locus Identity 0%
Counterpart found

GreenMonkey

TCONS_00003650

Exonic Identity 25%

Locus Identity 29%
Counterpart found

Marmoset

TCONS_00031137

Exonic Identity 0%

Locus Identity 0%
Counterpart not found

Lemur

ENST00000619449

Human non-coding transcript

Open the region of interest in the ENSEMBL Browser

ENSEMBL Browser

Check the reference ENSEMBL
transcript ID

ENSEMBL Transcript

Open the region of interest in the UCSC Genome Browser

UCSC Genome Browser